Blocking fatty acids slows prostate cancer

Blocking fatty acids slows prostate cancer

Medicine shows that fatty acids fuel prostate tumor growth. As blocking fatty acids seems to slow disease progression, fatty acid uptake may be a promising new therapeutic target for prostate cancer.

Renea Taylor, the deputy director of the Cancer Program at the Monash Biomedicine Discovery Institute in Clayton, Australia, and Prof. Matthew Watt, the head of the Physiology Department at the University of Melbourne, also in Australia, led the new research.

As Taylor, Prof. Watt, and their colleagues mention in their paper, even though prostate cancer grows slowly, preventing it from reaching an aggressive stage remains difficult.

The researchers wondered what it is that causes prostate tumors to become so aggressive. They wanted to determine what fuels the tumors and how prostate cancer metabolism differs from that of other cancers

Taylor explains what pointed the researchers in the direction of fatty acids. "There is a strong link between obesity, diet, and poor outcomes in men who develop prostate cancer," she says.

"In particular, those men who consume more saturated fatty acids seem to have more aggressive cancer."

So, the scientists set out to examine more closely the role of fatty acids in prostate tumor growth.

Fasting boosts metabolism and fights aging

Fasting boosts metabolism and fights aging

The latest study to explore the impact of fasting on the human body concludes that it increases metabolic activity more than previously realized and may even impart anti-aging benefits.

Studies have shown that intermittent fasting can help certain people lose weight.

Although researchers are still debating exactly how effective fasting can be for weight loss, new research hints at other benefits.

In rats, for instance, studies show that fasting can increase lifespan.

Although exciting, evidence of this in humans has yet to be seen.

The most recent study — which the authors have now published in the journal Scientific Reports — takes a fresh look at fasting in humans and provides new insight.

"Recent aging studies have shown that caloric restriction and fasting have a prolonging effect on lifespan in model animals," says first study author Dr. Takayuki Teruya, "but the detailed mechanism has remained a mystery."

In particular, scientists at the Okinawa Institute of Science and Technology Graduate University in Japan examined its impact on metabolism.

By understanding the metabolic processes involved, the team hopes to find ways of harnessing the benefits of fasting without the need to go without food for prolonged periods.

To investigate, they fasted four volunteers for 58 hours. Using metabolomics, or the measurement of metabolites, the researchers analyzed whole blood samples at intervals during the fasting period.

Choosing the right vitamins for you

Choosing the right vitamins for you

We have experienced taking vitamins at some point in our lives, even if the vitamins are from our local health center. However, with a lot of vitamins available in the market now, the process of choosing the right multi for you can be overwhelming.

It’s ultimately up to you and your physician to determine whether taking a multivitamin is right for you. There are many options out there but here are some of the guidelines to help navigate the multivitamin maze. Look for:

1. Appropriate daily values of ingredients

Choose a multivitamin with 100%of the daily value of most of its ingredients. Some nutrients, such as calcium, can’t be included in a multivitamin at 100% – if it was, the multivitamin would be too large to swallow. Magnesium and potassium levels are kept low to avoid drug-nutrient interactions, so we need to get these nutrients primarily through our diet (see food sources below.). Keep in mind, too, that exceeding 100% of the daily value of certain nutrients is not helpful. Some nutrients – like vitamins A, D, E, and K – can build up in the body and become toxic.

2. The right balance for your age and sex

Nutrient needs vary depending on gender and age. For example, premenopausal women need more iron, while older adults need more calcium, vitamin D, and B6. A dietician or your family doctor can help you determine how much specific nutrients you need for your age and gender.

3. Essential micronutrients

Your body needs micronutrients to keep your systems humming. Besides well-known nutrients like vitamin C, calcium, iron, magnesium, and potassium, a good multivitamin will include:

1.Thiamin, riboflavin, and niacin

2.B6, B12, and folate

3.Calcium, magnesium, selenium, and zinc

4.Vitamins A (including beta carotene), E, and K

5.Vitamin D2 or D3

You can skip multivitamins that are made with additional micronutrients for which there are no recommended daily values (examples: boron, nickel, and tin).

4. The nutrients you need

According to the Dietary Guidelines for Americans 2020-2025, American diets often lack calcium, vitamin D, potassium, and fiber. Most multivitamins contain 100% of the daily value for vitamin D, but have limited amounts of calcium and potassium and no fiber. Therefore, even if you take a multivitamin, it’s important to consume foods rich in these nutrients:

1.Calcium: Low-fat milk, cheese, and yogurt; calcium-fortified, plant-based milks; orange juice; cereals; tofu (prepared with calcium citrate); and almonds

2.Vitamin D: salmon, enriched milk (cow or plant-based), fortified orange juice, or cereals and yogurt

3.Potassium: Beans and legumes; potatoes; low-fat milk and yogurt; lower-sodium canned tomato products; fruits; and lamb, pork, and fish

4.Fiber: Beans and legumes; nuts and seeds; oats and whole grains; and fruits and vegetables

5.Magnesium: Nuts and seeds, avocado, spinach, dry beans, whole grains, and oats.

 

Source: Rodder, S., (2021, January, 20). 5 signs you’ve chosen the right multivitamin. UTSouthwestern Medical Center. https://utswmed.org/medblog/multivitamins-supplements/

 

 

Commute precautions during the COVID-19 pandemic

Commute precautions during the COVID-19 pandemic

The ongoing Covid-19 pandemic situation has improved over the months. Workers are now going back to their offices. With so much uncertainty about public transport, how can you protect yourself from the Covid-19?

The more individualized safety suggestions are to your particular city or town, the better. Here are a few general precautions that should apply across the board:

Maintain a safe social distance if possible. Naturally, when busses or subways don’t have room there’s not much you can do. But if there is space, stay as distant from other passengers as you can.

Change your commute time. If possible, shift your commute to non-peak hours in order to reduce the congestion you encounter during your commute. Also, consider giving yourself some extra commute time in case you need to wait for a less busy bus or train to arrive.

Sanitize and wash your hands often. It’s important to sanitize your hands before and after your trip.

Wear a mask. Cloth coverings can help slow the spread.

Source: Janzer, C. (2020, May, 26). Getting to Work During a Pandemic. Workest by Zenefits. https://www.zenefits.com/workest/getting-to-work-during-a-pandemic/

Do you need 8 glasses of water everyday?

Do you need 8 glasses of water everyday?

Your body is about 60 percent water.

With continuous activities every day, how much water do you really need to keep yourself from dehydration? Many studies have been conducted over the years and experts recommend 8 glasses of water every day, but in truth, your water intake depends on many factors, including daily activity, where you live, and your health status.

Although there is no single prescribed formula for your water intake, knowing yourself will help you to estimate how much water you need to drink each day.

You might need to modify your water intake based on several factors:

Exercise. If you do any activity that makes you sweat, you need to drink extra water to cover the fluid loss. It's important to drink water before, during, and after a workout.

Environment. Hot or humid weather can make you sweat and requires additional fluid. Dehydration also can occur at high altitudes.

Overall health. Your body loses fluids when you have a fever, vomiting or diarrhea. Drink more water or follow a doctor's recommendation to drink oral rehydration solutions. Other conditions that might require increased fluid intake include bladder infections and urinary tract stones.

Pregnancy and breast-feeding. If you are pregnant or breast-feeding, you may need additional fluids to stay hydrated.

Most healthy people can stay hydrated by drinking water and other fluids whenever they feel thirsty. For some people, fewer than eight glasses a day might be enough, but other people might need more. Your fluid intake is probably adequate if you rarely feel thirsty and the color of your urine is colorless or light yellow.

Source: Mayoclinic.(2020, October, 14). Water: How much should you drink every day? https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/water/art-20044256

 

Why wash your hands?

Why wash your hands?

Your mobile phone, pen, and paper, your desk keyboard, are just some of the helpful tools we always reach for to finish our job. But these useful tools also bring terrible germs with them especially if these are for public use.

Washing hands can keep you healthy and prevent the spread of respiratory and diarrheal infections from one person to the next. Germs can spread from other people or surfaces when you:

1.Touch your eyes, nose, and mouth with unwashed hands

2.Prepare or eat food and drinks with unwashed hands

3.Touch a contaminated surface or objects

4.Blow your nose, cough, or sneeze into hands and then touch other people’s hands or common objects

You can help yourself and your loved ones stay healthy by washing your hands often, especially during these key times when you are likely to get and spread germs:

Before, during, and after preparing

foodBefore and after eating

foodBefore and after caring for someone at home who is sick with vomiting or diarrhea

Before and after treating a cut or wound

After using the toilet

After changing diapers or cleaning up a child who has used the toilet

After blowing your nose, coughing, or sneezing

After touching an animal, animal feed, or animal waste

After handling pet food or pet treats

After touching garbage

Follow Five Steps to Wash Your Hands the Right Way

Washing your hands is easy, and it’s one of the most effective ways to prevent the spread of germs. Clean hands can stop germs from spreading from one person to another and throughout an entire community—from your home and workplace to childcare facilities and hospitals.

Follow these five steps every time.

Wet your hands with clean, running water (warm or cold), turn off the tap, and apply soap.

Lather your hands by rubbing them together with the soap. Lather the backs of your hands, between your fingers, and under your nails.

Scrub your hands for at least 20 seconds. Need a timer? Hum the “Happy Birthday” song from beginning to end twice.

Rinse your hands well under clean, running water.

Dry your hands using a clean towel or air dry them.

Source: Centers for Disease Control and Prevention. (2019, December, 4). Handwashing & Nail Hygiene. https://www.cdc.gov/healthywater/hygiene/hand/handwashing.html

Shopping During Covid-19 Pandemic

Shopping During Covid-19 Pandemic

Covid-19 is an unprecedented transformation in the way we live. It has killed millions globally and changed the way we live day-to-day. One aspect of this is the way we buy our essential needs, as traveling physically extends the risk of you getting the virus itself.

During the rapid spread of Covid-19, stores were forced to close down because of poor sales and overall low supply. This shifted the market to other means by adapting to other methods of sale such as online shopping and courier deliveries.

If you need to enter a store with no other alternatives at the ready, it is recommended to go during off-hours when there will likely be fewer people. Wear a mask and stay at least 6 feet away from others. Try to spend as little time as possible when you're shopping. You might need to gear up as a preventive measure against the virus. Wearing face masks, face shields, and sanitizers is the new normal moving forward.

With all these preventive measures, it doesn't eliminate the risk of catching the virus. Some shoppers can still enter the store passing the health declaration protocol and temperature check at the entrance, but the person can still be infected but not show any early signs of the virus.

With the Covid-19 pandemic still ongoing, you and your family's safety should be your priority. If your essentials can be ordered online, order them online and only go out if there is no absolute choice.

It is indeed an unfortunate year the world is experiencing. While our experts are finding ways to defeat the virus, it is smart to limit your exposure to the outside world and practice social distancing.

 

Reference:

The Associated Press. (2020, December, 1). Is shopping in stores safe during the pandemic? APNews. https://apnews.com/article/is-shopping-in-stores-safe-pandemic-750300666d2de740c0117f5dcc8ad34a

Common Colds, Flu, Coronavirus: How to Tell the Difference?

Common Colds, Flu, Coronavirus: How to Tell the Difference?

When colder air sets in, flu season inches closer to everyone. Fever, chills, body aches, and cough. All the symptoms seem the same for a cold, the flu, seasonal allergies, and coronavirus, also known as COVID-19. How do you know the difference?

The Ohio State University, Wexner Medical Center, listed and compared the symptoms of common colds and flu to coronavirus.

Coronavirus / COVID-19 symptoms:

  • Dry cough (can be severe)
  • Fever
  • Shortness of breath
  • Difficulty breathing (in severe cases)
  • Loss of taste and/or smell

 

Influenza symptoms:

  • Dry cough
  • Fever
  • Body aches
  • Headache
  • Fatigue

 

Common cold symptoms:

  • Cough, wet or dry
  • Sneezing
  • Body aches
  • Sore throat
  • Stuffy or runny nose
  • Watery eyes

Unlike colds or coronavirus, vaccination is a good way to prevent the flu. If you received a flu shot and still get it, your symptoms are generally milder than if you didn’t receive the flu shot. Most people with the sickness get well without medical treatment. Stay home and get plenty of rest and fluids and treat a fever with acetaminophen (Tylenol) or ibuprofen (Advil, Motrin).

It’s important to remember that antibiotics won’t help any viral infections. Usually, the infections just need to run their course, so it’s best to just wait and watch.  If your viral symptoms get better, and then days later suddenly get worse, you should contact your healthcare provider who can evaluate whether you may have a bacterial infection.

If you believe you have symptoms and might be infected with COVID-19, it’s best to be safe and get tested.

References:

Tolliver, S., (2020, September, 11), A cold, the flu or COVID-19: What’s the difference? The Ohio State University, Wexner Medical Center. https://wexnermedical.osu.edu/blog/cold-flu-or-covid-19

Intermountain Healthcare. (2020, September, 22). What's the difference between a cold, the flu, seasonal allergies and coronavirus? Intermountainhealthcare. https://intermountainhealthcare.org/blogs/topics/live-well/2020/03/whats-the-difference-between-a-cold-the-flu-and-coronavirus/

Does buying Generic Medicines Mean Lower Quality?

Does buying Generic Medicines Mean Lower Quality?

When you shop for your essentials, which aisle do you go to? Do you like comparing and checking each detail of your products? Or do you specifically ask for known brands straight away?

Consumers have more access to information than ever before, thanks to our mobile devices and the abundant and more efficient use of the internet nowadays. They fill the gaps in their knowledge when they consider and choose their products especially their health needs.

This puts us in a dilemma when tasked to purchase medicines, as consumers usually have options to choose from: branded and generic medicines. Generic medicines are usually cheaper, but does that mean that it isn’t as effective as its branded counterpart? Let’s take a closer look at the difference between these two are:

What are branded medicines?

branded medicine is the original product that has been developed by a pharmaceutical company. When a company develops a new medicine, their product must undergo and pass rigorous tests and evaluations to ensure that it is both effective in curing the condition it claims to treat and safe for human use. Because pharmaceutical companies invest considerable amounts of money to develop a new medicine, they are given the sole right to manufacture and distribute the medicine for a period of time.

What are generic medicines?

A generic medicine is a copy of the original branded product. Once the patent for the original product has run out, the pharmaceutical company that developed the medicine no longer has the exclusive right to produce and distribute the medicine. Other pharmaceutical companies are able to create their own version of the medicine.

In conclusion, generic medicines are those which contain the same active ingredient (the ingredient which acts to cure the condition) in the same quantity as a brand-name medicine.

Does cheaper just mean lower quality? That might be the initial response of consumers when shopping for household tools, but not for your medical needs such as medicines. Generic medicines have the same effect on the body in terms of curing disease as the brand-name medicines which they copy. It’s all based on personal preference, but as long as the generic medicine is used widely, then it should have the same effect as a branded one.

 

Reference:

 

Health Engine. (2009, April, 8). Generic medicines and branded medicines. https://healthengine.com.au/info/generic-medicines-and-branded-medicines